Hereditary Non Polyposis Colorectal Carcinoma Registry of Puerto Rico

Registro de Cancer de Colon No Asociado a Poliposis de Puerto Rico

Contents

• Puerto Rico Hereditary Non Polyposis Cololrectal Cancer Registry/Registro de Cancer de Colon No Asociado a Poliposis de Puerto Rico
• What is Hereditary Non Polyposis Colorectal Cancer?/Que es Cancer de Colon No Asociado a Poliposis?
• HNPCC Syndromes: Defined/Definicion del los Sindromes de CCNAP
• Which Families should be evaluated?/Que familias deben de ser evaluadas?
• Information/Informacion
• Comments and Suggestions/Comentarios y Sugerencias
• Contact Information/Donde conectarse para mas informacion

Puerto Rico Hereditary Non Polyposis Colorectal Cancer Registry

Since October 16,1997 a Registry for Families with Hereditary Non Polyposis Colorectal Cancer was developed at Ryder Memorial Hospital by Dr. Rafael A. Mosquera in Humacao, Puerto Rico, with the help of Dr. Henry T. Lynch, Director of the Hereditary Cancer Institute at Crieghton School of Medicine in Omaha, Nebraska.

Our objectives are to identify families with this type of hereditary colon cancer, develop a pedigree of the family so that the colorectal cancer risk can be determined; orient them on screening techniques available, depending on their risk and helping them to understand it. Families with this condition are evaluated for germ line mutations, a genetic test available through the Registry free of charge

Registro de Cancer de Colon No Asociado a Poliposis de Puerto Rico

El dia 16 de octubre de 1997 se inaguro el Registro de Familias con Cancer de Colon No Asociado a Poliposis desarollado en el Hospital Ryder Memorial por el Dr. Rafael A. Mosquera en Humacao, Puerto Rico, con la ayuda de el Dr. Henry T. Lynch, Director del Instituto de Cancer Hereditario en la Escuela de Medicina de la Universidad de Creighton, Omaha, Nebrasca.

Los objetivos del Registro son identificar familias con cancer de colon hereditario, desarollar su arbol familiar, de forma que se pueda determinar su riesgo a desarrollar cancer; orientarlas en cuanto a las tecnicas de evaluacion dependiendo de su riesgo y ayudarlas a entender su condicion. En adicion si tiene la condicion, ofrecerle los estudios de mutaciones de celulas germinales, una prueba de sangre que nos ayuda a determinar su riesgo, la cual es libre de costo atraves del Registro.

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What is Hereditary Non Polyposis Colorectal Cancer?

• HNPCC is a condition, that has been identified in some famililies, where there is a predisposition to inherit colon, rectal, small bowel, gastric, gallbladder, pancreas, ureter, urinary bladder, ovaries, and uterine cancers. It was described by Dr. Henry T. Lynch, Director of the Hereditary Cancer Institute at Creighton University School of Medicine , Omaha, Nebraska.

Que es Cancer de Colon Hereditario No Asociado a Poliposis?

• CCHNAP es una condicion. identificada en algunas familias, donde existe una predispocision a heredar cancer de colon, recto,intestino delgado, vesicula, pancreas, ureter, vejiga urinaria, ovarios y de utero. Fue descrita por el Dr. Henry T. Lynch,Director del Instituto de Cancer Hereditario en la Escuela de Medicina de la Universidad de Creighton, Omaha, Nebrasca.

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HNPCC Syndromes:Defined

1. Lynch Syndrome type I - Hereditary condition in which there is a high incidence of gastrointestinal malignancies.
2. .Lynch Syndrome type II - Hereditary condition in which there is a high incidence of gastrointestinal, genitourinary , uterine and ovaries cancers.

Definicion del Sindrome(CCHNAP)

1. Sindrome de Lynch tipo I - Condicion hereditaria que predispone a desarrollar malignidades en el tracto gastrointestinal ( todo el intestino)
2. Sindrome de Lynch tipo II - Condicion hereditaria que predispone a desarrollar malignidades en el tracto gastrointestinal y en adicion malignidades en utero, ovarios,vejiga urinaria y ureteres.

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Which Families should be evaluated?

Patients with colorectal cancer at young ages ( below 50y/o) with direct family members with colorectal cancers or any of the above mentioned malignancies.

Que familias deben de ser evaluadas:

Pacientes con cancer colorectal ( intestino o cualquier parte del tracto gastrointestinal) con familiares directos con canceres como los descritos anteriormente. Muchos tios, tias, papa,mama,hermano, hermana, abuelo,abuela con uno de los canceres mencionados anteriormente.

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Puerto Rico HNPCC Registry

Rafael A. Mosquera, M.D.

Gastroenterologist

Director of Puerto Rico HNPCC Registry

Ryder Memorial Hospital, Inc. Humacao, Puerto Rico

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Comments and Suggestions

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Contact Information:

Mail address:mosquera@caribe.net
Web address:http://netdial.caribe.net/~mosquera/
Ryder Memorial Hospital, Inc.

Other sites on colon cancer information::

http://cancer.med.upenn.edu/forms/listserv.htm#colon

http://www.cancergenetics.org/home.htm

http://info.med.yale.edu/ycc/cgupdate/fall98md.htm

http://www.salick.com/resource/site02.htm

http://www.ahamade.com/CancerSurvivors/page37.htm

http://www.cancer-info.com/colon.htm

http://cancernet.nci.nih.gov/clinpdq/pif/Colon cancer Patient.htm

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